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Crohn's disease

Disease information

Crohn's disease is an inflammatory bowel disease (IBD). More than 2 million Europeans and 1ยท5 million North Americans have inflammatory bowel disease (IBD). It causes inflammation of your digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition.

Inflammation caused by Crohn's disease can involve different areas of the digestive tract in different people. The inflammation caused by Crohn's disease often spreads deep into the layers of affected bowel tissue. Crohn's disease can be both painful and debilitating, and sometimes may lead to life-threatening complications. While there's no known cure for Crohn's disease, therapies can greatly reduce its signs and symptoms and even bring about long-term remission. With treatment, many people with Crohn's disease are able to function well.

Risk factors for Crohn's disease may include age, ethnicity, family history, smoking, medications, and general lifestyle.

Demographics

Total samples: 71
Females: 20
Males: 50
Age: 28.4 (5-48)
BMI: 18.7 (13.2-24.9)

Species association

Enriched in 76 species
Depleted in 162 species

Cohorts

hgma06 - Crohn's disease - China

hgma17 - Crohn's disease - Spain

Bioprojects included

PRJEB15371 - 10.1093/gigascience/gix050

PRJEB2054 - 10.1038/nature08821

Relative abundance

Phylum
Family
Genus

Richness overview

Gene

Species

Richness overview (per cohort)

Gene

Species