ko00010 - Glycolysis / Gluconeogenesis

ko00020 - Citrate cycle (TCA cycle)

ko00030 - Pentose phosphate pathway

ko00040 - Pentose and glucuronate interconversions

ko00051 - Fructose and mannose metabolism

ko00052 - Galactose metabolism

ko00053 - Ascorbate and aldarate metabolism

ko00061 - Fatty acid biosynthesis

ko00071 - Fatty acid degradation

ko00130 - Ubiquinone and other terpenoid-quinone biosynthesis

ko00230 - Purine metabolism

ko00240 - Pyrimidine metabolism

ko00250 - Alanine, aspartate and glutamate metabolism

ko00260 - Glycine, serine and threonine metabolism

ko00270 - Cysteine and methionine metabolism

ko00281 - Geraniol degradation

ko00290 - Valine, leucine and isoleucine biosynthesis

ko00300 - Lysine biosynthesis

ko00330 - Arginine and proline metabolism

ko00340 - Histidine metabolism

ko00350 - Tyrosine metabolism

ko00360 - Phenylalanine metabolism

ko00400 - Phenylalanine, tyrosine and tryptophan biosynthesis

ko00410 - beta-Alanine metabolism

ko00440 - Phosphonate and phosphinate metabolism

ko00450 - Selenocompound metabolism

ko00460 - Cyanoamino acid metabolism

ko00471 - D-Glutamine and D-glutamate metabolism

ko00473 - D-Alanine metabolism

ko00480 - Glutathione metabolism

ko00500 - Starch and sucrose metabolism

ko00511 - Other glycan degradation

ko00520 - Amino sugar and nucleotide sugar metabolism

ko00521 - Streptomycin biosynthesis

ko00540 - Lipopolysaccharide biosynthesis

ko00550 - Peptidoglycan biosynthesis

ko00564 - Glycerophospholipid metabolism

ko00620 - Pyruvate metabolism

ko00630 - Glyoxylate and dicarboxylate metabolism

ko00640 - Propanoate metabolism

ko00650 - Butanoate metabolism

ko00660 - C5-Branched dibasic acid metabolism

ko00670 - One carbon pool by folate

ko00710 - Carbon fixation in photosynthetic organisms

ko00720 - Carbon fixation pathways in prokaryotes

ko00730 - Thiamine metabolism

ko00740 - Riboflavin metabolism

ko00750 - Vitamin B6 metabolism

ko00760 - Nicotinate and nicotinamide metabolism

ko00770 - Pantothenate and CoA biosynthesis

ko00780 - Biotin metabolism

ko00785 - Lipoic acid metabolism

ko00790 - Folate biosynthesis

ko00791 - Atrazine degradation

ko00900 - Terpenoid backbone biosynthesis

ko00903 - Limonene and pinene degradation

ko00910 - Nitrogen metabolism

ko00920 - Sulfur metabolism

ko00970 - Aminoacyl-tRNA biosynthesis

ko00983 - Drug metabolism - other enzymes

ko01040 - Biosynthesis of unsaturated fatty acids

ko01053 - Biosynthesis of siderophore group nonribosomal peptides

ko01110 - Biosynthesis of secondary metabolites

ko02010 - ABC transporters

ko02020 - Two-component system

ko02030 - Bacterial chemotaxis

ko02040 - Flagellar assembly

ko02060 - Phosphotransferase system (PTS)

ko03030 - DNA replication

ko03060 - Protein export

ko03070 - Bacterial secretion system

ko03410 - Base excision repair

ko03430 - Mismatch repair

ko03440 - Homologous recombination

ko05111 - Biofilm formation - Vibrio cholerae

M00002 - Glycolysis, core module involving three-carbon compounds

M00003 - Gluconeogenesis, oxaloacetate => fructose-6P

M00004 - Pentose phosphate pathway (Pentose phosphate cycle)

M00005 - PRPP biosynthesis, ribose 5P => PRPP

M00006 - Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P

M00007 - Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P

M00008 - Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate

M00009 - Citrate cycle (TCA cycle, Krebs cycle)

M00010 - Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate

M00011 - Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate

M00012 - Glyoxylate cycle

M00015 - Proline biosynthesis, glutamate => proline

M00016 - Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine

M00017 - Methionine biosynthesis, apartate => homoserine => methionine

M00018 - Threonine biosynthesis, aspartate => homoserine => threonine

M00019 - Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine

M00020 - Serine biosynthesis, glycerate-3P => serine

M00021 - Cysteine biosynthesis, serine => cysteine

M00022 - Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate

M00033 - Ectoine biosynthesis, aspartate => ectoine

M00034 - Methionine salvage pathway

M00045 - Histidine degradation, histidine => N-formiminoglutamate => glutamate

M00048 - Inosine monophosphate biosynthesis, PRPP + glutamine => IMP

M00049 - Adenine ribonucleotide biosynthesis, IMP => ADP,ATP

M00050 - Guanine ribonucleotide biosynthesis IMP => GDP,GTP

M00053 - Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP

M00060 - Lipopolysaccharide biosynthesis, KDO2-lipid A

M00061 - D-Glucuronate degradation

M00063 - CMP-KDO biosynthesis

M00064 - ADP-L-glycero-D-manno-heptose biosynthesis

M00086 - beta-Oxidation, acyl-CoA synthesis

M00093 - Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE

M00096 - C5 isoprenoid biosynthesis, non-mevalonate pathway

M00115 - NAD biosynthesis, aspartate => NAD

M00116 - Menaquinone biosynthesis, chorismate => menaquinol

M00117 - Ubiquinone biosynthesis, prokaryotes, chorismate => ubiquinone

M00119 - Pantothenate biosynthesis, valine/L-aspartate => pantothenate

M00121 - Heme biosynthesis, glutamate => heme

M00123 - Biotin biosynthesis, pimeloyl-ACP/CoA => biotin

M00124 - Pyridoxal biosynthesis, erythrose-4P => pyridoxal-5P

M00127 - Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P

M00133 - Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine

M00134 - Polyamine biosynthesis, arginine => ornithine => putrescine

M00144 - NADH

M00149 - Succinate dehydrogenase, prokaryotes

M00150 - Fumarate reductase, prokaryotes

M00153 - Cytochrome bd ubiquinol oxidase

M00157 - F-type ATPase, prokaryotes and chloroplasts

M00165 - Reductive pentose phosphate cycle (Calvin cycle)

M00167 - Reductive pentose phosphate cycle, glyceraldehyde-3P => ribulose-5P

M00176 - Assimilatory sulfate reduction, sulfate => H2S

M00308 - Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P

M00338 - Cysteine biosynthesis, homocysteine + serine => cysteine

M00364 - C10-C20 isoprenoid biosynthesis, bacteria

M00365 - C10-C20 isoprenoid biosynthesis, archaea

M00417 - Cytochrome o ubiquinol oxidase

M00432 - Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

M00525 - Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine

M00526 - Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine

M00527 - Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine

M00533 - Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate

M00535 - Isoleucine biosynthesis, pyruvate => 2-oxobutanoate

M00549 - Nucleotide sugar biosynthesis, glucose => UDP-glucose

M00550 - Ascorbate degradation, ascorbate => D-xylulose-5P

M00552 - D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P

M00554 - Nucleotide sugar biosynthesis, galactose => UDP-galactose

M00555 - Betaine biosynthesis, choline => betaine

M00565 - Trehalose biosynthesis, D-glucose 1P => trehalose

M00570 - Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine

M00572 - Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP

M00573 - Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin

M00577 - Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin

M00631 - D-Galacturonate degradation (bacteria)

M00632 - Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P

M00641 - Multidrug resistance, efflux pump MexEF-OprN

M00642 - Multidrug resistance, efflux pump MexJK-OprM

M00696 - Multidrug resistance, efflux pump AcrEF-TolC

M00697 - Multidrug resistance, efflux pump MdtEF-TolC

M00698 - Multidrug resistance, efflux pump BpeEF-OprC

M00700 - Multidrug resistance, efflux pump AbcA

M00702 - Multidrug resistance, efflux pump NorB

M00704 - Tetracycline resistance, efflux pump Tet38

M00714 - Multidrug resistance, efflux pump QacA

M00718 - Multidrug resistance, efflux pump MexAB-OprM

M00746 - Multidrug resistance, repression of porin OmpF

M00761 - Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N

M00793 - dTDP-L-rhamnose biosynthesis

M00843 - L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4

M00844 - Arginine biosynthesis, ornithine => arginine

M00845 - Arginine biosynthesis, glutamate => acetylcitrulline => arginine

M00846 - Siroheme biosynthesis, glutamate => siroheme

AA10

CBM34

CBM48

CBM5

CBM50

CBM73

GH1

GH102

GH103

GH105

GH108

GH127

GH13_10

GH13_11

GH13_16

GH13_18

GH13_19

GH13_21

GH13_26

GH13_29

GH13_5

GH13_9

GH153

GH154

GH18

GH19

GH2

GH20

GH23

GH24

GH28

GH3

GH31

GH32

GH36

GH37

GH38

GH4

GH43_11

GH43_26

GH5_13

GH65

GH73

GH77

GH8

GH88

GT1

GT17

GT19

GT2

GT20

GT26

GT28

GT30

GT35

GT4

GT5

GT51

GT56

GT83

GT9

PL22

Actin-based motility

Adhesion

Bile resistance

Biofilm

Cell motility

Cell surface and membrane proteins

Cell-to-cell spread

Cellular metabolism

Chaperone

Defense against host immune response

Drug efflux system

Fimbriae

Intracellular survival and replication

Invasion

Iron uptake

Lps (lipopolysaccharide)

Modulate host immune response

Protease

Regulation of gene expression

Stress

Two-component system

Virulence

Zinc uptake

16 kDa heat shock protein A (ID:SL1344_3776)

16 kDa heat shock protein B (ID:c4606)

2-ketobutyrate formate-lyase (EC 2.3.1.-) @ Pyruvate formate-lyase (EC 2.3.1.54) (ID:Z4466)

3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (ID:S0967)

3'-to-5' exoribonuclease RNase R (ID:S4602)

4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (EC 5.3.1.17) (ID:STM474_3165)

ABC transporter protein IroC (ID:APECO1_O1CoBM140)

Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) (ID:STM14_4260)

ATP-dependent helicase HrpA (ID:Z2313)

BarA-associated response regulator UvrY (= GacA = SirA) (ID:SL1344_1877)

Biosynthetic arginine decarboxylase (EC 4.1.1.19) (ID:Z4283)

Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) (ID:Z0038)

Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) (ID:Z0037)

Carbon starvation protein A (ID:SL1344_0588)

Chorismate synthase (EC 4.2.3.5) (ID:t0480)

Colanic acid biosynthesis glycosyl transferase WcaE (ID:STM474_2196)

Curli production assembly/transport component CsgF (ID:SL1344_1077)

Curli production assembly/transport component CsgG (ID:STM14_1303)

Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) (ID:SL1344_0436)

D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (ID:Z4251)

D-sedoheptulose 7-phosphate isomerase (EC 5.3.1.28) (ID:SL1344_0306)

D-tagatose-1,6-bisphosphate aldolase subunit KbaY (EC 4.1.2.40) (ID:b3137)

Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1), subgroup 1 (ID:SL1344_0209)

Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) (ID:c1081)

Dipeptide ABC transporter, substrate-binding protein DppA (TC 3.A.1.5.2) @ Dipeptide chemoreceptor (ID:c4361)

DNA polymerase IV (EC 2.7.7.7) (ID:SL1344_0309)

DNA-binding transcriptional dual regulator SoxS (ID:STM14_5127)

DTDP-4-amino-4,6-dideoxygalactose transaminase (EC 2.6.1.59) (ID:c4711)

DTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) (ID:STM14_2590)

DTDP-glucose 4,6-dehydratase (EC 4.2.1.46) (ID:STM14_2591)

Exonuclease SbcD (ID:STM474_0413)

FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) (ID:SL1344_0257)

FKBP-type peptidyl-prolyl cis-trans isomerase FkpA precursor (EC 5.2.1.8) (ID:STM3453)

FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) (ID:STM474_3621)

Formate efflux transporter FocA (ID:SL1344_0911)

Galactose/methyl galactoside ABC transporter, ATP-binding protein MglA (EC 3.6.3.17) (ID:Z3404)

Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) (ID:SL1344_2072)

Glycosyltransferase IroB (ID:APECO1_O1CoBM141)

GMP synthase [glutamine-hydrolyzing], amidotransferase subunit (EC 6.3.5.2) / GMP synthase [glutamine-hydrolyzing], ATP pyrophosphatase subunit (EC 6.3.5.2) (ID:S2725)

GTP-binding and nucleic acid-binding protein YchF (ID:c1661)

Hha toxicity modulator TomB (ID:STM474_0494)

Holliday junction ATP-dependent DNA helicase RuvB (EC 3.6.4.12) (ID:SL1344_1828)

Homoserine O-succinyltransferase (EC 2.3.1.46) (ID:SL1344_4117)

Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I (ID:SEN2801)

Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I (ID:SG2866)

Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain (ID:STM2511)

Lipid A biosynthesis myristoyltransferase (EC 2.3.1.243) (ID:SFK218_2097)

Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (ID:SL1344_1747)

Maltodextrin ABC transporter, ATP-binding protein MsmX (ID:Z2463)

Manganese ABC transporter, ATP-binding protein SitB (ID:c1599)

Manganese ABC transporter, periplasmic-binding protein SitA (ID:SF1365)

Methyl-directed repair DNA adenine methylase (EC 2.1.1.72) (ID:SL1344_3451)

Monothiol glutaredoxin GrxD (ID:E2348C_1740)

Multidrug efflux pump MdfA/Cmr (of MFS type), broad spectrum (ID:STM14_1016)

Murein peptide ABC transporter, substrate-binding protein (requires DppBCDF) (ID:c1803)

N,N'-diacetylchitobiose-specific 6-phospho-beta-glucosidase (EC 3.2.1.86) (ID:STM474_1321)

Na+/H+-dicarboxylate symporter (ID:Z4942)

NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) (ID:STM2323.S)

Osmolarity sensory histidine kinase EnvZ (ID:STM14_4216)

Outer membrane porin OmpC (ID:SF2299)

Outer membrane porin OmpD (ID:SL1344_1503)

Outer membrane protein A precursor (ID:b0957)

Outer Membrane Siderophore Receptor IroN (ID:APECO1_O1CoBM137)

Outer-membrane-phospholipid-binding lipoprotein MlaA (ID:S2559)

Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34) (ID:SL1344_0566)

Peptidyl-prolyl cis-trans isomerase PpiC (EC 5.2.1.8) (ID:SL1344_3870)

Periplasmic beta-glucosidase (EC 3.2.1.21) (ID:SL1344_2144)

Periplasmic chaperone and peptidyl-prolyl cis-trans isomerase of outer membrane proteins SurA (EC 5.2.1.8) (ID:SF0050)

Periplasmic chaperone of outer membrane proteins Skp @ Outer membrane protein H precursor (ID:SF2457T_4958)

Phosphate transport system regulatory protein PhoU (ID:c4648)

Phosphomannomutase (EC 5.4.2.8) => Colanic acid (ID:c2557)

Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (ID:STM14_5016)

Probable endopeptidase NlpC (ID:SL1344_1277)

Protein MtfA (ID:STM474_2081)

PTS system, galactitol-specific IIC component (ID:b2092)

PTS system, N,N'-diacetylchitobiose-specific IIB component (EC 2.7.1.196) (ID:SL1344_1247)

Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) (ID:STM474_0956)

Respiratory nitrate reductase alpha chain (EC 1.7.99.4) (ID:b1224)

RNA polymerase-binding transcription factor DksA (ID:S0140)

SbmA protein (ID:c0482)

Sensor histidine kinase PhoQ (EC 2.7.13.3) (ID:STM14_1408)

Signal transduction histidine-protein kinase BarA (EC 2.7.13.3) (ID:SL1344_2939)

Spermidine export protein MdtJ (ID:SL1344_1412)

Stress response diiron-containing protein YciF (ID:STM474_1746)

Stringent starvation protein A (ID:STM14_4033)

Superoxide dismutase [Fe] (EC 1.15.1.1) (ID:SFV_1678)

Thioredoxin 2 (ID:Z3867)

Threonine catabolic operon transcriptional activator TdcA (ID:SL1344_3217)

TolA protein (ID:SL1344_0729)

TonB-dependent receptor; Outer membrane receptor for ferric enterobactin and colicins B, D (ID:STM14_0682)

Transcriptional regulatory protein PhoP (ID:SF1149)

Transketolase (EC 2.2.1.1) (ID:c3520)

Translation initiation factor SUI1-related protein (ID:SL1344_1638)

Trilactone hydrolase IroD (ID:APECO1_O1CoBM139)

Trk potassium uptake system protein TrkA (ID:Z4660)

Tryptophan synthase beta chain (EC 4.2.1.20) (ID:Z2550)

Type IV pilin PilA (ID:Z0118)

UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (EC 2.3.1.191) (ID:STM0226)

UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (ID:SL1344_2057)

Uncharacterized ferredoxin-like protein YfhL (ID:SL1344_2538)

Uncharacterized protease YegQ (ID:SL1344_2112)

Uncharacterized protein YjaG (ID:SL1344_4108)

Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.33) (ID:S3902)

UPF0118 inner membrane protein YdiK (ID:SL1344_1298)

UPF0187 protein YneE (ID:STM474_1538)

UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (ID:S1322)

UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (ID:SL1344_2075)

Zinc ABC transporter, ATP-binding protein ZnuC (ID:STM14_2301)

Zinc ABC transporter, permease protein ZnuB (ID:STM14_2302)

Zinc ABC transporter, substrate-binding protein ZnuA (ID:STM14_2300)

Aryl Polyene

Non-ribosomal peptide synthetase (NRPS)

Siderophore