| Species: | Klebsiella oxytoca |
|---|---|
| Genus: | Klebsiella |
| Family: | Enterobacteriaceae |
| Order: | Enterobacterales |
| Class: | Gammaproteobacteria |
| Phylum: | Proteobacteria |
| Gut outflow: | 1 |
|---|---|
| Disease Association: |
Type 2 diabetes (ES=0.748266) |
| Shape | Rod-shaped |
|---|---|
| Gram staining | Gram- |
| Motility | Motile |
| Oxygen Requirement | Facultative; Microaerophilic |
| Sporulation | Nonsporulating |
| Ecosystem | Human; Terrestrial; Mammals |
| Ecosystem Type | Skin; Respiratory system; Unclassified; Soil; Circulatory system; Excretory system |
In the linked pathways:
red=enriched, blue=depleted
ko00010 - Glycolysis / Gluconeogenesis
ko00020 - Citrate cycle (TCA cycle)
ko00030 - Pentose phosphate pathway
ko00040 - Pentose and glucuronate interconversions
ko00051 - Fructose and mannose metabolism
ko00052 - Galactose metabolism
ko00053 - Ascorbate and aldarate metabolism
ko00061 - Fatty acid biosynthesis
ko00071 - Fatty acid degradation
ko00130 - Ubiquinone and other terpenoid-quinone biosynthesis
ko00230 - Purine metabolism
ko00240 - Pyrimidine metabolism
ko00250 - Alanine, aspartate and glutamate metabolism
ko00260 - Glycine, serine and threonine metabolism
ko00270 - Cysteine and methionine metabolism
ko00281 - Geraniol degradation
ko00290 - Valine, leucine and isoleucine biosynthesis
ko00300 - Lysine biosynthesis
ko00330 - Arginine and proline metabolism
ko00340 - Histidine metabolism
ko00350 - Tyrosine metabolism
ko00360 - Phenylalanine metabolism
ko00362 - Benzoate degradation
ko00364 - Fluorobenzoate degradation
ko00400 - Phenylalanine, tyrosine and tryptophan biosynthesis
ko00410 - beta-Alanine metabolism
ko00430 - Taurine and hypotaurine metabolism
ko00440 - Phosphonate and phosphinate metabolism
ko00450 - Selenocompound metabolism
ko00460 - Cyanoamino acid metabolism
ko00471 - D-Glutamine and D-glutamate metabolism
ko00473 - D-Alanine metabolism
ko00480 - Glutathione metabolism
ko00500 - Starch and sucrose metabolism
ko00511 - Other glycan degradation
ko00520 - Amino sugar and nucleotide sugar metabolism
ko00521 - Streptomycin biosynthesis
ko00540 - Lipopolysaccharide biosynthesis
ko00550 - Peptidoglycan biosynthesis
ko00561 - Glycerolipid metabolism
ko00564 - Glycerophospholipid metabolism
ko00620 - Pyruvate metabolism
ko00622 - Xylene degradation
ko00630 - Glyoxylate and dicarboxylate metabolism
ko00640 - Propanoate metabolism
ko00650 - Butanoate metabolism
ko00660 - C5-Branched dibasic acid metabolism
ko00670 - One carbon pool by folate
ko00710 - Carbon fixation in photosynthetic organisms
ko00720 - Carbon fixation pathways in prokaryotes
ko00730 - Thiamine metabolism
ko00740 - Riboflavin metabolism
ko00750 - Vitamin B6 metabolism
ko00760 - Nicotinate and nicotinamide metabolism
ko00770 - Pantothenate and CoA biosynthesis
ko00780 - Biotin metabolism
ko00785 - Lipoic acid metabolism
ko00790 - Folate biosynthesis
ko00791 - Atrazine degradation
ko00860 - Porphyrin and chlorophyll metabolism
ko00900 - Terpenoid backbone biosynthesis
ko00903 - Limonene and pinene degradation
ko00910 - Nitrogen metabolism
ko00920 - Sulfur metabolism
ko00930 - Caprolactam degradation
ko00970 - Aminoacyl-tRNA biosynthesis
ko00983 - Drug metabolism - other enzymes
ko01040 - Biosynthesis of unsaturated fatty acids
ko01053 - Biosynthesis of siderophore group nonribosomal peptides
ko01110 - Biosynthesis of secondary metabolites
ko01120 - Microbial metabolism in diverse environments
ko01130 - Biosynthesis of antibiotics
ko02010 - ABC transporters
ko02020 - Two-component system
ko02030 - Bacterial chemotaxis
ko02060 - Phosphotransferase system (PTS)
ko03030 - DNA replication
ko03060 - Protein export
ko03070 - Bacterial secretion system
ko03410 - Base excision repair
ko03430 - Mismatch repair
ko03440 - Homologous recombination
ko05111 - Biofilm formation - Vibrio cholerae
M00002 - Glycolysis, core module involving three-carbon compounds
M00003 - Gluconeogenesis, oxaloacetate => fructose-6P
M00004 - Pentose phosphate pathway (Pentose phosphate cycle)
M00005 - PRPP biosynthesis, ribose 5P => PRPP
M00006 - Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
M00007 - Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P
M00008 - Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate
M00009 - Citrate cycle (TCA cycle, Krebs cycle)
M00010 - Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00012 - Glyoxylate cycle
M00015 - Proline biosynthesis, glutamate => proline
M00016 - Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00017 - Methionine biosynthesis, apartate => homoserine => methionine
M00018 - Threonine biosynthesis, aspartate => homoserine => threonine
M00019 - Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00020 - Serine biosynthesis, glycerate-3P => serine
M00021 - Cysteine biosynthesis, serine => cysteine
M00022 - Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate
M00033 - Ectoine biosynthesis, aspartate => ectoine
M00034 - Methionine salvage pathway
M00035 - Methionine degradation
M00045 - Histidine degradation, histidine => N-formiminoglutamate => glutamate
M00048 - Inosine monophosphate biosynthesis, PRPP + glutamine => IMP
M00050 - Guanine ribonucleotide biosynthesis IMP => GDP,GTP
M00051 - Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP
M00053 - Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP
M00060 - Lipopolysaccharide biosynthesis, KDO2-lipid A
M00061 - D-Glucuronate degradation
M00063 - CMP-KDO biosynthesis
M00064 - ADP-L-glycero-D-manno-heptose biosynthesis
M00083 - Fatty acid biosynthesis, elongation
M00086 - beta-Oxidation, acyl-CoA synthesis
M00093 - Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE
M00096 - C5 isoprenoid biosynthesis, non-mevalonate pathway
M00115 - NAD biosynthesis, aspartate => NAD
M00116 - Menaquinone biosynthesis, chorismate => menaquinol
M00117 - Ubiquinone biosynthesis, prokaryotes, chorismate => ubiquinone
M00119 - Pantothenate biosynthesis, valine/L-aspartate => pantothenate
M00121 - Heme biosynthesis, glutamate => heme
M00122 - Cobalamin biosynthesis, cobinamide => cobalamin
M00123 - Biotin biosynthesis, pimeloyl-ACP/CoA => biotin
M00124 - Pyridoxal biosynthesis, erythrose-4P => pyridoxal-5P
M00127 - Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P
M00133 - Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine
M00134 - Polyamine biosynthesis, arginine => ornithine => putrescine
M00136 - GABA biosynthesis, prokaryotes, putrescine => GABA
M00144 - NADH
M00149 - Succinate dehydrogenase, prokaryotes
M00150 - Fumarate reductase, prokaryotes
M00153 - Cytochrome bd ubiquinol oxidase
M00157 - F-type ATPase, prokaryotes and chloroplasts
M00165 - Reductive pentose phosphate cycle (Calvin cycle)
M00167 - Reductive pentose phosphate cycle, glyceraldehyde-3P => ribulose-5P
M00176 - Assimilatory sulfate reduction, sulfate => H2S
M00338 - Cysteine biosynthesis, homocysteine + serine => cysteine
M00364 - C10-C20 isoprenoid biosynthesis, bacteria
M00365 - C10-C20 isoprenoid biosynthesis, archaea
M00417 - Cytochrome o ubiquinol oxidase
M00432 - Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
M00525 - Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
M00526 - Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527 - Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
M00533 - Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate
M00535 - Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
M00545 - Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
M00549 - Nucleotide sugar biosynthesis, glucose => UDP-glucose
M00550 - Ascorbate degradation, ascorbate => D-xylulose-5P
M00551 - Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol
M00552 - D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P
M00554 - Nucleotide sugar biosynthesis, galactose => UDP-galactose
M00555 - Betaine biosynthesis, choline => betaine
M00565 - Trehalose biosynthesis, D-glucose 1P => trehalose
M00568 - Catechol ortho-cleavage, catechol => 3-oxoadipate
M00570 - Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
M00572 - Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP
M00573 - Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin
M00577 - Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin
M00579 - Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate
M00631 - D-Galacturonate degradation (bacteria)
M00632 - Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P
M00642 - Multidrug resistance, efflux pump MexJK-OprM
M00696 - Multidrug resistance, efflux pump AcrEF-TolC
M00698 - Multidrug resistance, efflux pump BpeEF-OprC
M00714 - Multidrug resistance, efflux pump QacA
M00718 - Multidrug resistance, efflux pump MexAB-OprM
M00740 - Methylaspartate cycle
M00761 - Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N
M00793 - dTDP-L-rhamnose biosynthesis
M00843 - L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4
M00844 - Arginine biosynthesis, ornithine => arginine
M00845 - Arginine biosynthesis, glutamate => acetylcitrulline => arginine
M00846 - Siroheme biosynthesis, glutamate => siroheme
M00855 - Glycogen degradation, glycogen => glucose-6P
Actin-based motility
Adherence
Adhesion
Bile resistance
Biofilm
Cell motility
Cell surface and membrane proteins
Cell-to-cell spread
Cellular metabolism
Chaperone
Drug efflux system
Escape from the phagosome
Intracellular survival and replication
Invasion
Lps (lipopolysaccharide)
Modulate host immune response
Protease
Regulation of gene expression
Secretion
Stress
Virulence
Zinc uptake
16 kDa heat shock protein A (ID:SL1344_3776)
16 kDa heat shock protein B (ID:c4606)
3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (ID:S0967)
3'-to-5' exoribonuclease RNase R (ID:S4602)
Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) (ID:STM14_4260)
ATP-dependent helicase HrpA (ID:Z2313)
BarA-associated response regulator UvrY (= GacA = SirA) (ID:SL1344_1877)
Biosynthetic arginine decarboxylase (EC 4.1.1.19) (ID:Z4283)
Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) (ID:Z0038)
Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) (ID:Z0037)
Carbon starvation protein A (ID:SL1344_0588)
CFA/I fimbrial major subunit (ID:Z0360)
Chaperone protein FimC (ID:c5395)
Chorismate synthase (EC 4.2.3.5) (ID:t0480)
Cobyrinic acid a,c-diamide synthetase (EC 6.3.5.11) (ID:SG2061)
Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) (ID:SL1344_0436)
D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (ID:Z4251)
D-sedoheptulose 7-phosphate isomerase (EC 5.3.1.28) (ID:SL1344_0306)
Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1), subgroup 1 (ID:SL1344_0209)
Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) (ID:c1081)
Dipeptide ABC transporter, substrate-binding protein DppA (TC 3.A.1.5.2) @ Dipeptide chemoreceptor (ID:c4361)
DNA polymerase IV (EC 2.7.7.7) (ID:SL1344_0309)
DNA-binding transcriptional dual regulator SoxS (ID:STM14_5127)
DTDP-4-amino-4,6-dideoxygalactose transaminase (EC 2.6.1.59) (ID:c4711)
Ferric uptake regulation protein FUR (ID:SEN0657)
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA precursor (EC 5.2.1.8) (ID:STM3453)
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) (ID:STM474_3621)
Formate efflux transporter FocA (ID:SL1344_0911)
Galactose/methyl galactoside ABC transporter, ATP-binding protein MglA (EC 3.6.3.17) (ID:Z3404)
GMP synthase [glutamine-hydrolyzing], amidotransferase subunit (EC 6.3.5.2) / GMP synthase [glutamine-hydrolyzing], ATP pyrophosphatase subunit (EC 6.3.5.2) (ID:S2725)
Hha toxicity modulator TomB (ID:STM474_0494)
Holliday junction ATP-dependent DNA helicase RuvB (EC 3.6.4.12) (ID:SL1344_1828)
Homoserine O-succinyltransferase (EC 2.3.1.46) (ID:SL1344_4117)
Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I (ID:SG2866)
Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain (ID:S2726)
Lipid A biosynthesis myristoyltransferase (EC 2.3.1.243) (ID:SFK218_2097)
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (ID:SL1344_1747)
Low-affinity inorganic phosphate transporter (ID:Z4341)
Lysine/cadaverine antiporter membrane protein CadB (ID:STM474_2663)
Manganese ABC transporter, periplasmic-binding protein SitA (ID:SL1344_2841)
Methyl-directed repair DNA adenine methylase (EC 2.1.1.72) (ID:SL1344_3451)
Mg(2+) transport ATPase, P-type (EC 3.6.3.2) (ID:STM14_4536)
Monothiol glutaredoxin GrxD (ID:E2348C_1740)
Multidrug efflux pump MdfA/Cmr (of MFS type), broad spectrum (ID:STM14_1016)
Murein peptide ABC transporter, substrate-binding protein (requires DppBCDF) (ID:c1803)
N,N'-diacetylchitobiose-specific 6-phospho-beta-glucosidase (EC 3.2.1.86) (ID:STM474_1321)
Na+/H+-dicarboxylate symporter (ID:Z4942)
NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) (ID:STM2323.S)
Outer membrane protein A precursor (ID:c1093)
Outer membrane usher protein FimD (ID:c5396)
Outer-membrane-phospholipid-binding lipoprotein MlaA (ID:S2559)
Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34) (ID:SL1344_0566)
Peptidyl-prolyl cis-trans isomerase PpiC (EC 5.2.1.8) (ID:SL1344_3870)
Periplasmic beta-glucosidase (EC 3.2.1.21) (ID:SL1344_2144)
Periplasmic chaperone and peptidyl-prolyl cis-trans isomerase of outer membrane proteins SurA (EC 5.2.1.8) (ID:SF0050)
Periplasmic chaperone of outer membrane proteins Skp @ Outer membrane protein H precursor (ID:SF2457T_4958)
Periplasmic thiol:disulfide interchange protein DsbA (ID:SFV_3641)
Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation (ID:c1633)
Phosphate transport system regulatory protein PhoU (ID:c4648)
Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (ID:STM14_5016)
Probable endopeptidase NlpC (ID:SL1344_1277)
Probable metabolite transport protein (ID:SL1344_0513)
Protein MtfA (ID:STM474_2081)
PTS system, galactitol-specific IIB component (EC 2.7.1.200) (ID:b2093)
PTS system, galactitol-specific IIC component (ID:b2092)
PTS system, N,N'-diacetylchitobiose-specific IIB component (EC 2.7.1.196) (ID:SL1344_1247)
Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) (ID:STM474_0956)
Respiratory nitrate reductase alpha chain (EC 1.7.99.4) (ID:b1224)
RNA polymerase sigma factor RpoS (ID:SEN2763)
RNA polymerase-binding transcription factor DksA (ID:S0140)
SbmA protein (ID:c0482)
Signal transduction histidine-protein kinase BarA (EC 2.7.13.3) (ID:SL1344_2939)
Spermidine export protein MdtJ (ID:SL1344_1412)
Stress response diiron-containing protein YciF (ID:STM474_1746)
Stringent starvation protein A (ID:STM14_4033)
Superoxide dismutase [Fe] (EC 1.15.1.1) (ID:SFV_1678)
Thioredoxin 2 (ID:Z3867)
TolA protein (ID:SL1344_0729)
Transketolase (EC 2.2.1.1) (ID:c3520)
Translation initiation factor SUI1-related protein (ID:SL1344_1638)
Trk potassium uptake system protein TrkA (ID:Z4660)
Tryptophan synthase beta chain (EC 4.2.1.20) (ID:Z2550)
Type IV pilin PilA (ID:Z0118)
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (EC 2.3.1.191) (ID:STM0226)
UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (ID:SL1344_2057)
Uncharacterized ferredoxin-like protein YfhL (ID:SL1344_2538)
Uncharacterized protease YegQ (ID:SL1344_2112)
Uncharacterized protein YjaG (ID:SL1344_4108)
Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.33) (ID:S3902)
Universal stress protein F (ID:STM474_1664)
Ureidoglycolate dehydrogenase (EC 1.1.1.154) (ID:SL1344_0521)
UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (ID:S1322)
UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (ID:SL1344_2075)
Zinc ABC transporter, ATP-binding protein ZnuC (ID:STM14_2301)
Zinc ABC transporter, permease protein ZnuB (ID:STM14_2302)
Zinc ABC transporter, substrate-binding protein ZnuA (ID:STM14_2300)
Ladderane
Non-ribosomal peptide synthetase (NRPS)
Other secondary metabolites
MATLAB species model file: msp_0140.mat
